Parkinson S Stem Cell Treatment Clinical Trials

With all clinical trials ensuring that the treatment is safe and effective is paramount and along with the international research community we will be watching the progress of the trial very. Isco a california based clinical stage biotechnology company developing stem cell based therapies and biomedical products announced today the positive six months interim results of the first cohort of parkinson s disease pd patients receiving 30 million isc hpnsc cells in the ongoing clinical study. Each of the four centers is planning a clinical trial to start in the next 1 4 years.

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Parkinson s stem cell treatment clinical trials.

After years of study stem cell treatments which involve transplanting cells to replace the brain cells lost in pd are being tested in clinicaltrials around the world. But that doesn t mean we shouldn t be forging ahead using stem cells to discover more about the disease in order to find new drugs as well as refine our ideas about transplantation. Yesterday a team of neurologists neurosurgeons and stem cell biologists from across multiple institutions reported results of a stem cell trial involving one person with parkinson s in the new england journal of medicine the trial also was covered by top science reporter sharon begley of stat. This clinical trial under way at the royal melbourne hospital in australia is designed to demonstrate the safety of isc hpnsc as a treatment for parkinson s disease.

Parkinson s uk has invested more than 3 million in cutting edge stem cell research to help develop new and better treatments for parkinson s faster. Patient enrollment and dosing is now complete for international stem cell corporation s isco phase 1 trial testing its isc hpnsc neural stem cells a cellular therapy that offers a new approach for treating parkinson s disease. But the history of these therapies has been fraught with confusion and disappointment. In the first of its kind study the patient s own stem cells were turned into dopamine.

Four groups dedicated to using stem cell therapies to treat parkinson s disease have formed an international consortium known as g force pd. The future of stem cell therapy for parkinson s. And medical therapy for parkinson s is so advanced that transplantation right now probably isn t going to be any better than what we can already do. How can people with parkinson s disease pd assess the safety of clinical trials for stem cell therapies.

In the phase i trial three groups of four patients will each receive a specific dose of isc hpnsc ranging from 30 000 000 to 70 000 000 neural stem cells. We are excited to announce the completion of enrollment of the world s first approved human pluripotent stem cell based clinical trial for the treatment.

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